CDC34 anticorps

N° du produit ABIN6941292

Cet anticorps Souris Monoclonal détecte spécifiquement CDC34 dans IHC et StM. Il présente une réactivité envers Humain.

Aperçu rapide pour CDC34 anticorps (ABIN6941292)

Antigène: CDC34 (Cell Division Cycle 34 (CDC34))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC34 est non-conjugé

Application: Immunohistochemistry (IHC), Staining Methods (StM)

Clone: CPTC-CDC34-2

Détail du produit anti-CDC34 anticorps

Purification: Purified by Protein A/G

Immunogène: Recombinant human full-length CDC34 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: 293, K562, Jurkat cell lysates. Human small intestine.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CDC34

Antigène: CDC34 (Cell Division Cycle 34 (CDC34))

Autre désignation: CDC34

Sujet: Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B and Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation and has been shown to form a stable complex with HSP 90. Cdc34, Cdc27 and Cdc16 function as ubiquitinconjugating enzymes. Cdc34 is thought to be the structural and functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 and Cdc27 are components of the APC (anaphasepromoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation.

Poids moléculaire: 34kDa

ID gène: 997

UniProt: P49427