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CA 19-9 anticorps

L’anticorps Lapin Monoclonal anti-CA 19-9 a été validé pour IHC et StM. Il convient pour détecter CA 19-9 dans des échantillons de Humain.
N° du produit ABIN6941454

Aperçu rapide pour CA 19-9 anticorps (ABIN6941454)

Antigène

Voir toutes CA 19-9 Anticorps
CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Reactivité

  • 42
  • 1
  • 1
Humain

Hôte

  • 28
  • 14
  • 2
Lapin

Clonalité

  • 41
  • 2
Monoclonal

Conjugué

  • 27
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CA 19-9 est non-conjugé

Application

  • 25
  • 18
  • 17
  • 16
  • 8
  • 8
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Staining Methods (StM)

Clone

CA19-9-1390R
  • Specificité

    CA19-9, a carbohydrate epitope expressed on a high MW (400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.

    Immunogène

    Purified human CA19-9 protein

    Isotype

    IgG
  • Indications d'application

    Positive Control: Stomach or Colon Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (5-10 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions

    For Research Use only
  • Concentration

    200 μg/mL

    Buffer

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-80 °C

    Stockage commentaire

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    Date de péremption

    24 months
  • Antigène

    CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

    Autre désignation

    CA19-9/Sialyl Lewisa (GI Tumor Marker)

    Poids moléculaire

    >400kDa
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