PD-1 anticorps
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- Antigène Voir toutes PD-1 (PDCD1) Anticorps
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reactivité
- Souris
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Hôte
- Rat
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PD-1 est non-conjugé
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Application
- Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Neutralization (Neut), Coating (Coat)
- Aucune reactivité croisée
- Humain
- Purification
- Purified by Protein A/G
- Immunogène
- PDCD1 transfected BHK cells
- Clone
- RMP1-14
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product PDCD1 Anticorps primaire
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- Indications d'application
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Positive Control: Spleen, Thymus or Lymph Node.
Known Application: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Autre désignation
- PDCD1 (PDCD1 Produits)
- Synonymes
- anticorps CD279, anticorps PD-1, anticorps PD1, anticorps SLEB2, anticorps hPD-1, anticorps hPD-l, anticorps Ly101, anticorps Pdc1, anticorps programmed cell death 1, anticorps PDCD1, anticorps Pdcd1
- Sujet
- PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally,Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells).
- Poids moléculaire
- 50-55kDa
- ID gène
- 18566
- UniProt
- Q02242
- Pathways
- Cancer Immune Checkpoints
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