Recombinant BANF1 anticorps

N° du produit ABIN6942215

Cet anticorps anti-BANF1 Monoclonal Lapin (ABIN6942215) détecte spécifiquement BANF1 dans IF, ICC, IHC (p) et IHC (fro). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant BANF1 anticorps (ABIN6942215)

Antigène: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BANF1 est non-conjugé

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BANF1 anticorps

Fonction: BANF1 Recombinant Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Full length recombinant protein of human BANF1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur BANF1

Antigène: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Autre désignation: BANF1

Sujet:

Synonyms: Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor N-terminally processed, BANF1, BAF, BCRG1, NGPS, BCRP1,

Background: Barrier-to-autointegration factor (BANF1) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BANF1 compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BANF1 from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

ID gène: 8815

UniProt: O75531