BAZ1B anticorps
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- Antigène Voir toutes BAZ1B Anticorps
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BAZ1B est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant protein within C-terminal human BAZ1B.
- Clone
- 5G1
- Isotype
- IgG
- Top Product
- Discover our top product BAZ1B Anticorps primaire
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- Indications d'application
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WB 1:300-5000
FCM 1:20-100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))
- Autre désignation
- BAZ1B (BAZ1B Produits)
- Synonymes
- anticorps BAZ1B, anticorps wstf, anticorps wbscr9, anticorps wbscr10, anticorps LOC100220420, anticorps WBSCR10, anticorps WBSCR9, anticorps WSTF, anticorps C87820, anticorps Wbscr9, anticorps fi60d02, anticorps im:7137554, anticorps wu:fi60d02, anticorps bromodomain adjacent to zinc finger domain 1B, anticorps bromodomain adjacent to zinc finger domain, 1B, anticorps bromodomain adjacent to zinc finger domain 1B S homeolog, anticorps BAZ1B, anticorps baz1b, anticorps Baz1b, anticorps baz1b.S
- Sujet
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Synonyms: Tyrosine-protein kinase BAZ1B, Bromodomain adjacent to zinc finger domain protein 1B, Williams syndrome transcription factor, Williams-Beuren syndrome chromosomal region 10 protein, Williams-Beuren syndrome chromosomal region 9 protein, hWALp2, BAZ1B, WBSC10, WBSCR10, WBSCR9, WSTF
Background: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.
- ID gène
- 9031
- UniProt
- Q9UIG0
- Pathways
- Nuclear Hormone Receptor Binding, Chromatin Binding
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