Calsequestrin anticorps

N° du produit ABIN6942360

Cet anticorps Lapin Monoclonal détecte spécifiquement Calsequestrin dans IF (cc), IHC (p) et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Calsequestrin anticorps (ABIN6942360)

Antigène: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Calsequestrin est non-conjugé

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 8G1

Détail du produit anti-Calsequestrin anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human Calsequestrin 1 aa 100-250

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Calsequestrin

Antigène: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Autre désignation: CASQ1

Sujet:

Synonyms: Calsequestrin 1, Calmitine, Calsequestrin skeletal muscle isoform, CASQ1, CASQ, PDIB1, VMCQA

Background: The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.

ID gène: 844

UniProt: P31415