CTU2 anticorps (AA 301-400)

N° du produit ABIN6942722

Cet anticorps anti-CTU2 est un anticorps Lapin Polyclonal détectant CTU2 dans WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) et ICC. Adapté pour Souris.

Aperçu rapide pour CTU2 anticorps (AA 301-400) (ABIN6942722)

Antigène: CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTU2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-CTU2 anticorps

Épitope: AA 301-400

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CTU2/C16orf84

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur CTU2

Antigène: CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))

Autre désignation: CTU2

Sujet:

Synonyms: C16orf84, ctu2, CTU2_HUMAN, Cytoplasmic tRNA 2-thiolation protein 2, cytosolic thiouridylase subunit 2 homolog (S. pombe), NCS2, PF0432.

Background: CTU2 is a 515 amino acid cytoplasmic protein that plays a role in the 2-thiolation of mcm(5)S(2)U at wobble positions of tRNA. CTU2 forms a complex with CTU1 and Urm1, and may also form a separate heterodimer with CTU1 to ligate sulfur from thiocarboxylated Urm1 onto tRNA. Existing as three alternatively spliced isoforms, the gene encoding CTU2 maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

ID gène: 348180

UniProt: Q2VPK5