CYP2C19 anticorps (AA 201-300) (AbBy Fluor® 488)

N° du produit ABIN6942777

Cet anticorps Lapin Polyclonal détecte spécifiquement CYP2C19 dans WB, IF (cc) et IF (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CYP2C19 anticorps (AA 201-300) (AbBy Fluor® 488) (ABIN6942777)

Antigène: CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2C19 est conjugé à/à la AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-CYP2C19 anticorps (AbBy Fluor® 488)

Épitope: AA 201-300

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CYP2C19

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CYP2C19

Antigène: CYP2C19 (Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19))

Autre désignation: CYP2C19

Sujet:

Synonyms: AI266900, CYP2C, CYP2C19, CYP2C37, CYP2C50, Cyp2c54, CYP450-2C, CPCJ, CYPIIC17, CYPIIC19, EG404195, LOC293989, MGC109053, P450-11A, P450C2C, P450IIC19, CP2CJ_HUMAN Cytochrome P450 2C19, R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, CYPIIC17, CYPIIC19, Cytochrome P450-11A, Cytochrome P450-254C, Mephenytoin 4-hydroxylase.

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes and is responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram, and imipramine. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq]

ID gène: 1557

UniProt: P33261