Dynamin 1-Like anticorps (pSer616) (AbBy Fluor® 680)

N° du produit ABIN6943125

Cet anticorps Lapin Polyclonal détecte spécifiquement Dynamin 1-Like dans IF (cc) et IF (p). Il présente une réactivité envers Souris.

Aperçu rapide pour Dynamin 1-Like anticorps (pSer616) (AbBy Fluor® 680) (ABIN6943125)

Antigène: Dynamin 1-Like (DNM1L)

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 1-Like est conjugé à/à la AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Dynamin 1-Like anticorps (AbBy Fluor® 680)

Épitope: pSer616

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthesised phosphopeptide derived from human DRP1 around the phosphorylation site of Ser616

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Dynamin 1-Like

Antigène: Dynamin 1-Like (DNM1L)

Autre désignation: DRP1

Sujet:

Synonyms: DRP1 (phospho S616), p-DRP1 (phospho S616), P-DRP1 (Ser616), DLP1, dnm1l, DNM1L_HUMAN, Dnm1p/Vps1p-like protein, DVLP, Dymple, Dynamin 1 like, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin like protein, Dynamin related protein 1, Dynamin-1-like protein, Dynamin-like protein 4, Dynamin-like protein, Dynamin-like protein IV, Dynamin-related protein 1, DYNIV 11, FLJ41912, HdynIV, VPS1.

Background: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

ID gène: 10059

UniProt: O00429