EEFSEC anticorps (AA 21-120) (HRP)

N° du produit ABIN6943210

L’anticorps anti-EEFSEC Polyclonal Lapin est utilisé pour la détection de EEFSEC dans des échantillons de Humain. Il a été validé pour IHC (p) et IHC (fro).

Aperçu rapide pour EEFSEC anticorps (AA 21-120) (HRP) (ABIN6943210)

Antigène: EEFSEC (Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEFSEC est conjugé à/à la HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-EEFSEC anticorps (HRP)

Épitope: AA 21-120

Fonction: EEFSEC Polyclonal Antibody, HRP Conjugated

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EEFSEC

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EEFSEC

Antigène: EEFSEC (Eukaryotic Elongation Factor, Selenocysteine-tRNA-Specific (EEFSEC))

Autre désignation: EEFSEC

Sujet:

Synonyms: EFSEC, SELB_HUMAN_ Elongation factor for selenoprotein translation, Elongation factor sec, Eukaryotic elongation factor, selenocysteine tRNA specific, SELB, Selenocysteine specific elongation factor.

Background: EEFSEC is a 596 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the GTP-binding elongation factor family. Functioning as a translation factor, SELB binds GTP and GDP and is necessary for the incorporation of selenocysteine into target proteins. The gene encoding SELB maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

ID gène: 60678

UniProt: P57772