EXOC1 anticorps (AA 701-800) (AbBy Fluor® 594)

N° du produit ABIN6943334

Cet anticorps anti-EXOC1 est un anticorps Lapin Polyclonal détectant EXOC1 dans IF (cc) et IF (p). Adapté pour Rat.

Aperçu rapide pour EXOC1 anticorps (AA 701-800) (AbBy Fluor® 594) (ABIN6943334)

Antigène: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EXOC1 est conjugé à/à la AbBy Fluor® 594

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-EXOC1 anticorps (AbBy Fluor® 594)

Épitope: AA 701-800

Réactivité croisée: Rat

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human EXOC1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EXOC1

Antigène: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Autre désignation: EXOC1

Sujet:

Synonyms: BM-012, exoc1, EXOC1_HUMAN, Exocyst complex component 1, Exocyst complex component Sec3, FLJ10893, SEC3, SEC3 like 1, SEC3L1, SEC3P.

Background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Exo70, also known as EXOC7 (exocyst complex component 7), EXOC1 or 2-5-3p, is a 735 amino acid peripheral membrane protein that is a component of the exocyst complex. Localized to the cytoplasm and the cell membrane, Exo70 plays an essential role in the docking of exocystic vesicles to target sites on the plasma membrane and, specifically, may be involved in insulin-induced protein docking within the cell. Four isoforms of Exo70 are expressed due to alternative splicing events.

ID gène: 55763

UniProt: Q9NV70

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis