FKBP4 anticorps (AA 1-200)

N° du produit ABIN6943472

Cet anticorps anti-FKBP4 Monoclonal Lapin (Clone 12A5) (ABIN6943472) détecte spécifiquement FKBP4 dans WB, FACS, IHC (p), IF (p) et IF (cc). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FKBP4 anticorps (AA 1-200) (ABIN6943472)

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FKBP4 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 12A5

Détail du produit anti-FKBP4 anticorps

Épitope: AA 1-200

Fonction: FKBP4 (12A5) Monoclonal Antibody

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human FKBP52 aa 1-200.

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:200-400), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FKBP4

Antigène: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Autre désignation: FKBP4

Sujet:

Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP4, 51 kDa FK506-binding protein, 52 kDa FK506-binding protein, 59 kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, Immunophilin FKBP52, Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4 N-terminally processed, PPIase FKBP4, FKBP51, 52 kDa FKBP, FKBP-52, p59, FKBP-4, HBI

Background: Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

ID gène: 2288

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway