HPV16 E7 anticorps (AA 50-98) (PE)

N° du produit ABIN6943725

Cet anticorps Lapin Polyclonal détecte spécifiquement HPV16 E7 dans WB et FACS. Il présente une réactivité avec des échantillons de Virus.

Aperçu rapide pour HPV16 E7 anticorps (AA 50-98) (PE) (ABIN6943725)

Antigène: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Reactivité: Virus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HPV16 E7 est conjugé à/à la PE

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-HPV16 E7 anticorps (PE)

Épitope: AA 50-98

Specificité: This antibody may also detect HPV35-E7

Réactivité croisée: Humain, Virus

Réactivité croisée (Details): HPV16

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from middle of HPV16-E7

Isotype: IgG

Information d'application

Indications d'application: FCM(1:20-100)

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HPV16 E7

Antigène: HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))

Autre désignation: HPV16-E7

Classe de substances: Viral Protein

Sujet:

Synonyms: Protein E7, E7

Background: Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. Plays also a role in the inhibition of both antiviral and antiproliferative functions of host inteferon alpha.

ID gène: 1489079

UniProt: P03129