JNK1/JNK2/JNK3 anticorps

N° du produit ABIN6943853

Cet anticorps anti-JNK1/JNK2/JNK3 est un anticorps Lapin Monoclonal détectant JNK1/JNK2/JNK3 dans WB et IF (cc). Adapté pour Souris, Rat, Humain, Singe et Poisson zèbre (Danio rerio).

Aperçu rapide pour JNK1/JNK2/JNK3 anticorps (ABIN6943853)

Antigène: JNK1/JNK2/JNK3

Reactivité: Souris, Rat, Humain, Singe, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp JNK1/JNK2/JNK3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 3G7

Détail du produit anti-JNK1/JNK2/JNK3 anticorps

Réactivité croisée: Humain, Singe, Souris, Rat, Poisson zèbre (Danio rerio)

Purification: Purified by Protein A.

Immunogène: Human JNK1+JNK2+JNK3 between 1 to 400 amino acids

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur JNK1/JNK2/JNK3

Antigène: JNK1/JNK2/JNK3

Autre désignation: JNK1+JNK2+JNK3

Sujet:

Synonyms: C Jun kinase 2, c Jun N terminal kinase 1, c Jun N terminal kinase 2, c Jun N terminal kinase 3, c-Jun N-terminal kinase 1, JNK 46, JNK 55, JNK, JNK-46, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, JNK3 alpha protein kinase, JNK3, JNK3A, Jun kinase, JUN N terminal kinase, MAP kinase 10, MAP kinase 8, MAP kinase 9, MAP kinase p49 3F12, MAPK 10, MAPK 8, MAPK 9, MAPK10, mapk8, MAPK9, Mitogen activated protein kinase 10, Mitogen activated protein kinase 8, Mitogen activated protein kinase 8 isoformJNK1 alpha1, Mitogen activated protein kinase 8 isoform JNK1 beta2, Mitogen activated protein kinase 9, Mitogen-activated protein kinase 8, MK08_HUMAN, p493F12, p54a, p54aSAPK, p54bSAPK, PRKM10, PRKM8, PRKM9, SAPK, SAPK(beta), SAPK1, SAPK1a, SAPK1b, SAPK1c, Stress activated protein kinase 1, Stress activated protein kinase1a, Stress activated protein kinase 1b, Stress activated protein kinase 1c, Stress activated protein kinase beta, Stress activated protein kinase JNK1, Stressactivated protein kinase JNK2, Stress activated protein kinase JNK3, Stressactivated protein kinase 1c, Stress-activated protein kinase JNK1,

Background: c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83 % amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.

UniProt: P45983, P45984, P53779