Recombinant LGALS8 anticorps (AA 1-100)

N° du produit ABIN6943917

Cet anticorps Lapin Monoclonal détecte spécifiquement LGALS8 dans ICC, IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant LGALS8 anticorps (AA 1-100) (ABIN6943917)

Antigène: LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp LGALS8 est non-conjugé

Application: Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-LGALS8 anticorps

Épitope: AA 1-100

Fonction: Galectin 8 Recombinant Antibody

Réactivité croisée: Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: Synthetic peptide within human Galectin 8 aa 1-100

Isotype: IgG

Information d'application

Indications d'application: Flow-Cyt(1:50-100), ICC/IF(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur LGALS8

Antigène: LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))

Autre désignation: LGALS8

Sujet:

Synonyms: Galectin-8, Po66 carbohydrate-binding protein, Prostate carcinoma tumor antigen 1, Gal-8, Po66-CBP, PCTA-1, LGALS8

Background: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.

ID gène: 3964

UniProt: O00214