MECP2 anticorps

N° du produit ABIN6944061

Cet anticorps Lapin Polyclonal détecte spécifiquement MECP2 dans WB, ELISA et DB. Il présente une réactivité envers Humain.

Aperçu rapide pour MECP2 anticorps (ABIN6944061)

Antigène: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MECP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Dot Blot (DB)

Détail du produit anti-MECP2 anticorps

Réactivité croisée: Humain

Purification: Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.

Immunogène: Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
dot-blot()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 μg/μL

Buffer: PBS with 0.05 % sodium azide and 0.05 % Proclin300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MECP2

Antigène: MECP2 (Methyl CpG Binding Protein 2 (MECP2))

Autre désignation: MeCP2

Sujet:

Synonyms: Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein

Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

ID gène: 4204

UniProt: P51608

Pathways: Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane