MLKL anticorps (pSer345)

N° du produit ABIN6944093

Cet anticorps anti-MLKL est un anticorps Lapin Monoclonal détectant MLKL dans WB, IHC (p) et IF (cc). Adapté pour Souris.

Aperçu rapide pour MLKL anticorps (pSer345) (ABIN6944093)

Antigène: MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

Reactivité: Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MLKL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 7G4

Détail du produit anti-MLKL anticorps

Épitope: pSer345

Réactivité croisée: Souris

Purification: Purified by Protein A.

Immunogène: Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MLKL

Antigène: MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

Autre désignation: MLKL

Sujet:

Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl

Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

ID gène: 74568

UniProt: Q9D2Y4