MLKL anticorps (pSer345)
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- Antigène Voir toutes MLKL Anticorps
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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Épitope
- pSer345
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MLKL est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Réactivité croisée
- Souris
- Purification
- Purified by Protein A.
- Immunogène
- Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
- Clone
- 7G4
- Isotype
- IgG
- Top Product
- Discover our top product MLKL Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- Autre désignation
- MLKL (MLKL Produits)
- Synonymes
- anticorps MLKL, anticorps 9130019I15Rik, anticorps mixed lineage kinase domain like pseudokinase, anticorps mixed lineage kinase domain-like, anticorps MLKL, anticorps mlkl, anticorps Mlkl
- Sujet
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Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
- ID gène
- 74568
- UniProt
- Q9D2Y4
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