Recombinant N-Cadherin anticorps (AA 150-250)

N° du produit ABIN6944206

L’anticorps anti-N-Cadherin Monoclonal Lapin est utilisé pour la détection de N-Cadherin dans des échantillons de Humain. Il a été validé pour WB, IHC (p), IF (p) et IHC (fro).

Aperçu rapide pour Recombinant N-Cadherin anticorps (AA 150-250) (ABIN6944206)

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp N-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-N-Cadherin anticorps

Épitope: AA 150-250

Fonction: N Cadherin Recombinant Antibody

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant human N Cadherin between 150 to 250 amino acids

Isotype: IgG

Information d'application

Indications d'application: WB(WB(1:500-2000)), IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200)), IF(IHC-P)(IF(IHC-P)(1:50-200))

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur N-Cadherin

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Autre désignation: N Cadherin

Sujet:

Synonyms: Cadherin-2, CDw325, Neural cadherin, CD_antigen: CD325, N-cadherin, CDH2

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

ID gène: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane