NMDAR2A anticorps (pSer1232)

N° du produit ABIN6944293

L’anticorps Lapin Polyclonal anti-NMDAR2A a été validé pour ELISA, ICC, IF (cc), IF (p), IHC (p) et IHC (fro). Il convient pour détecter NMDAR2A dans des échantillons de Humain.

Aperçu rapide pour NMDAR2A anticorps (pSer1232) (ABIN6944293)

Antigène: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NMDAR2A est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NMDAR2A anticorps

Épitope: pSer1232

Specificité: This phosphorylated site is homologous to that of Ser1232 in Mouse and Rat.

Homologie: Human,Mouse,Rat,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur NMDAR2A

Antigène: NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))

Autre désignation: NMDAR2A

Sujet:

Synonyms: NMDAR2A (phospho S1232), p-NMDAR2A (phospho S1232), GRIN2B, Glutamate [NMDA] receptor subunit epsilon 1, Glutamate [NMDA] receptor subunit epsilon 2, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-2, GRIN2A, hNR2A, hNR3, N methyl D aspartate receptor subtype 2A, N methyl D aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2A, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDAR2A, NMDAR2B, NMDE2_HUMAN, NR2A, NR2B, NR3.

Background: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

ID gène: 2903

UniProt: Q12879

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity