ORC2 anticorps

N° du produit ABIN6944371

L’anticorps anti-ORC2 Monoclonal Souris est utilisé pour la détection de ORC2 dans des échantillons de Humain. Il a été validé pour WB et IF (cc).

Aperçu rapide pour ORC2 anticorps (ABIN6944371)

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ORC2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 5C3

Détail du produit anti-ORC2 anticorps

Réactivité croisée: Humain

Purification: Protein G purified monoclonal antibody in PBS containing 0.05% azide.

Immunogène: Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively

Isotype: IgG1

Information d'application

Indications d'application: WB 1:300-5000
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.6 μg/μL

Buffer: PBS with 0.05 % sodium azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur ORC2

Antigène: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Autre désignation: ORC2

Sujet:

Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2

Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.

ID gène: 4999

UniProt: Q13416