Recombinant Periostin anticorps (C-Term)

N° du produit ABIN6944485

L’anticorps anti-Periostin Monoclonal Lapin est utilisé pour la détection de Periostin dans des échantillons de Humain. Il a été validé pour WB, IHC (p), FACS, IHC (fro) et IF (p).

Aperçu rapide pour Recombinant Periostin anticorps (C-Term) (ABIN6944485)

Antigène: Periostin (POSTN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Periostin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Periostin anticorps

Épitope: C-Term

Fonction: Periostin Recombinant Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Human Perilipin-1 aa 400 to the C-terminus

Isotype: IgG

Information d'application

Indications d'application: WB(WB(1:500-2000)), FCM(FCM(1:20-50)), IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500)), IF(IHC-P)(IF(IHC-P)(1:100-500))

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur Periostin

Antigène: Periostin (POSTN)

Autre désignation: Periostin

Sujet:

Synonyms: Periostin, Osteoblast-specific factor 2, PN, OSF-2, POSTN, OSF2, PDLPOSTN.

Background: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta and alpha(V)beta integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor _ 1(TGF _ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

ID gène: 10631

UniProt: Q15063