Periostin anticorps
Aperçu rapide pour Periostin anticorps (ABIN6944485)
Antigène
Voir toutes Periostin (POSTN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Purification
- Purified by Protein A.
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Immunogène
- Human Perilipin-1 aa 400 to the C-terminus
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
FCM 1:20-100 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- Periostin (POSTN)
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Autre désignation
- Periostin
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Sujet
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Synonyms: Periostin, Osteoblast-specific factor 2, PN, OSF-2, POSTN, OSF2, PDLPOSTN.
Background: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for alpha(V)beta and alpha(V)beta integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor _ 1(TGF _ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.
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ID gène
- 10631
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UniProt
- Q15063
Antigène
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