Pro Caspase 3 anticorps
Aperçu rapide pour Pro Caspase 3 anticorps (ABIN6944660)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- pro Caspase 3 (12B1) Monoclonal Antibody
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Réactivité croisée
- Humain, Souris
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Purification
- Purified by Protein A.
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), FCM(1:50-200), IHC-P(1:200-400), IF(ICC)(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C for 12 months.
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Date de péremption
- 12 months
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- Pro Caspase 3
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Sujet
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Synonyms: Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CASP-3, CPP-32, SCA-1, CASP3
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
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ID gène
- 836
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UniProt
- P42574
Antigène
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