Pro Caspase 9 anticorps
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- Antigène
- Pro Caspase 9
- Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Inconjugué
- Application
- Flow Cytometry (FACS), Western Blotting (WB)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- Human Caspase-9 between 250 to 350 amino acids
- Clone
- 3T6
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
FCM 1:20-100 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- Pro Caspase 9
- Sujet
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Synonyms: Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
- ID gène
- 842
- UniProt
- P55211
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