RPS19 anticorps

N° du produit ABIN6944797

Détail du produit anti-RPS19 anticorps

Antigène: RPS19 (Ribosomal Protein S19 (RPS19))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RPS19 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Full length recombinant protein of RPS19

Clone: 1C1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RPS19

Antigène: RPS19 (Ribosomal Protein S19 (RPS19))

Autre désignation: RPS19 (RPS19 Produits)

Synonymes: anticorps DBA, anticorps DBA1, anticorps S19, anticorps Dsk3, anticorps 30S ribosomal protein S19, anticorps 40S ribosomal protein S19, anticorps ribosomal protein S19, anticorps rps19, anticorps rps-19, anticorps RPS19, anticorps Rps19

Sujet:

Synonyms: 40S ribosomal protein S19, Small ribosomal subunit protein eS19, RPS19.

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS19 is a ribosomal protein that is a component of the 40S subunit. RPS19 belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

ID gène: 6223

UniProt: P39019

Pathways: Positive Regulation of Immune Effector Process, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly