SF3B3 anticorps

N° du produit ABIN6944865

Détail du produit anti-SF3B3 anticorps

Antigène: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SF3B3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Recombinant protein within the C-terminus of human SF3B3.

Clone: 5F1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SF3B3

Antigène: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Autre désignation: SF3B3 (SF3B3 Produits)

Synonymes: anticorps GB11574, anticorps rse1, anticorps sap130, anticorps sf3b130, anticorps staf130, anticorps sf3b3, anticorps 1810061H24Rik, anticorps 5730409A01Rik, anticorps AA409318, anticorps D8Ertd633e, anticorps RSE1, anticorps SAP130, anticorps mKIAA0017, anticorps ik:tdsubc_2b2, anticorps wu:fb81f05, anticorps xx:tdsubc_2b2, anticorps zgc:55440, anticorps SF3b130, anticorps STAF130, anticorps splicing factor 3b subunit 3, anticorps splicing factor 3B subunit 3, anticorps splicing factor 3b, subunit 3, 130kDa, anticorps splicing factor 3b subunit 3 L homeolog, anticorps splicing factor 3b, subunit 3, anticorps SF3B3, anticorps LOC550935, anticorps sf3b3, anticorps Sf3b3, anticorps LOC100178056, anticorps sf3b3.L

Sujet:

Synonyms: Splicing factor 3B subunit 3, Pre-mRNA-splicing factor SF3b 130 kDa subunit, STAF130, Spliceosome-associated protein 130, SF3b130, SF3B3, SAP130

Background: SF3B is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130 (also known as SF3B3), SAP 145 and SAP 155. SF3B3, SAP 145 and SAP 155 are present in a protein complex in HeLa nuclear extracts and associate with one another. While SF3B3 and SAP 155 interact with each other (directly or indirectly) within this complex, SAP 49 and SAP 145 are known to interact directly with each other. Unexpectedly, the SAP 49-SAP 145 protein-protein interaction requires the amino-terminus of SAP 49, which contains two RNA-recognition motifs. The observation that SAP 49 and SAP 145 interact directly with both U2 snRNP and the pre-mRNA suggests that this protein complex plays a role in tethering U2 snRNP to the branch site.

ID gène: 23450

UniProt: Q15393