SRSF3 anticorps

N° du produit ABIN6944869

L’anticorps anti-SRSF3 Monoclonal Lapin est utilisé pour la détection de SRSF3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC (p) et IF (cc).

Aperçu rapide pour SRSF3 anticorps (ABIN6944869)

Antigène: SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SRSF3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 9C11

Détail du produit anti-SRSF3 anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: Full length recombinant protein.

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur SRSF3

Antigène: SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

Autre désignation: SFRS3

Sujet:

Synonyms: Serine/arginine-rich splicing factor 3, SRSF3, Pre-mRNA-splicing factor SRP20, Splicing factor arginine/serine-rich 3, SRP20

Background: Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export. RNA-binding is semi-sequence specific

ID gène: 6428

UniProt: P84103