STING/TMEM173 anticorps (C-Term)

N° du produit ABIN6945184

L’anticorps anti-STING/TMEM173 Monoclonal Lapin est utilisé pour la détection de STING/TMEM173 dans des échantillons de Humain. Il a été validé pour WB et FACS.

Aperçu rapide pour STING/TMEM173 anticorps (C-Term) (ABIN6945184)

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp STING/TMEM173 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 1B8

Détail du produit anti-STING/TMEM173 anticorps

Épitope: C-Term

Fonction: TMEM173 (1B8) Monoclonal Antibody

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: Recombinant protein within human TMEM173 aa 200 to the C-terminus

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:20-100)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 12 months

Détails sur STING/TMEM173

Antigène: STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

Autre désignation: TMEM173

Sujet:

Synonyms: Stimulator of interferon genes protein, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Transmembrane protein 173, hSTING, ERIS, hMITA, TMEM173, ERIS, MITA, STING.

Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.

ID gène: 340061

UniProt: Q86WV6

Pathways: Activation of Innate immune Response