STING/TMEM173 anticorps
-
- Antigène Voir toutes STING/TMEM173 (TMEM173) Anticorps
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp STING/TMEM173 est non-conjugé
-
Application
- Western Blotting (WB), Flow Cytometry (FACS)
- Réactivité croisée
- Humain
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant protein within human TMEM173 aa 200 to the C-terminus
- Clone
- 1B8
- Isotype
- IgG
- Top Product
- Discover our top product TMEM173 Anticorps primaire
-
-
- Indications d'application
-
WB 1:300-5000
FCM 1:20-100 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Autre désignation
- TMEM173 (TMEM173 Produits)
- Synonymes
- anticorps ERIS, anticorps MITA, anticorps MPYS, anticorps NET23, anticorps STING, anticorps 2610307O08Rik, anticorps Mita, anticorps RGD1562552, anticorps transmembrane protein 173, anticorps TMEM173, anticorps Tmem173
- Sujet
-
Synonyms: Stimulator of interferon genes protein, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Transmembrane protein 173, hSTING, ERIS, hMITA, TMEM173, ERIS, MITA, STING.
Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
- ID gène
- 340061
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
-