Versican anticorps
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- Antigène Voir toutes Versican (Vcan) Anticorps
- Versican (Vcan)
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Reactivité
- Souris, Humain
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Versican est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant protein within human Versican aa 3100-3300
- Clone
- 2G2
- Isotype
- IgG
- Top Product
- Discover our top product Vcan Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- Versican (Vcan)
- Autre désignation
- Versican (Vcan Produits)
- Synonymes
- anticorps br146, anticorps cspg2, anticorps cspg2a, anticorps sb:cb63, anticorps versican, anticorps CSPG2, anticorps Cspg2, anticorps wgn, anticorps ervr, anticorps pg-m, anticorps wgn1, anticorps Xversican, anticorps dcan, anticorps cspg2b, anticorps fb99b07, anticorps wu:fb99b07, anticorps ERVR, anticorps GHAP, anticorps PG-M, anticorps WGN, anticorps WGN1, anticorps 5430420N07Rik, anticorps 9430051N09, anticorps DPEAAE, anticorps NG2, anticorps PG-M(V0), anticorps PG-M(V1), anticorps hdf, anticorps versican a, anticorps versican, anticorps versican b, anticorps vcana, anticorps VCAN, anticorps Vcan, anticorps vcan, anticorps vcanb
- Sujet
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Synonyms: Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate-binding protein, Large fibroblast proteoglycan, PG-M, Chondroitin sulfate proteoglycan 2, GHAP, VCAN, CSPG2.
Background: Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a lectin-like sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycosaminoglycan chains. Accumulation around smooth muscle cells in lesions of atherosclerosis, suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may facilitate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels. The human versican gene maps to chromosome 5q14.3.
- ID gène
- 1462
- UniProt
- P13611
- Pathways
- Glycosaminoglycan Metabolic Process
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