WT1 anticorps (AA 50-250)

N° du produit ABIN6945391

L’anticorps anti-WT1 Monoclonal Lapin est utilisé pour la détection de WT1 dans des échantillons de Humain et Souris. Il a été validé pour IHC, WB, FACS, IHC (p) et IF (cc).

Aperçu rapide pour WT1 anticorps (AA 50-250) (ABIN6945391)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Clone: 9G6

Détail du produit anti-WT1 anticorps

Épitope: AA 50-250

Fonction: Wilms Tumor Protein (9G6) Monoclonal Antibody

Réactivité croisée: Humain, Souris

Purification: Purified by Protein A.

Immunogène: Human Wilms Tumor Protein between 50 to 250 amino acids

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(ICC)(1:50-200), IHC()

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: Wilms Tumor Protein

Sujet:

Synonyms: Wilms tumor protein, WT33, WT1

Background: Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).

ID gène: 7490

UniProt: P19544

Pathways: Tube Formation