Claudin 18 anticorps

N° du produit ABIN6950837

Cet anticorps anti-Claudin 18 Monoclonal Souris (ABIN6950837) détecte spécifiquement Claudin 18 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Claudin 18 anticorps (ABIN6950837)

Antigène: Claudin 18 (CLDN18)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Claudin 18 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Claudin 18 anticorps

Fonction: Claudin 18 mouse mAb

Specificité: The antibody can specifically recognize both human Claudin 18. 1 and Claudin 18. 2 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogène: A synthetic peptide corresponding to the amino acid region 150 - 261 of the human Claudin 18 protein.

Isotype: IgG

Information d'application

Indications d'application: IHC, 1:200-1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur Claudin 18

Antigène: Claudin 18 (CLDN18)

Autre désignation: Claudin 18

Sujet:

Synonyms: Claudin 18, Claudin-18, CLD18_HUMAN, CLDN18, SFTA5, SFTPJ

Background: Claudin 18 is a 27 kDa membrane protein, belonging to the tight junction protein family. It is highly specifically expressed in gastric epithelial cells, and almost not expressed in other normal tissues. Studies have shown that the expression of gastric tissue increases after cancer, and the abnormal expression in pancreatic cancer, lung cancer, esophageal cancer and ovarian cancer promotes the metastasis of cancer cells. Therefore, antibody based drugs against Claudin 18 can significantly improve the survival rate of patients.

Gene Name: CLDN18

Protein Name: Claudin 18

ID gène: 51208

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C