Histone H3.3 anticorps

N° du produit ABIN6952331

Cet anticorps Lapin Monoclonal détecte spécifiquement Histone H3.3 dans WB, ChIP et ChIP-seq. Il présente une réactivité envers Humain.

Aperçu rapide pour Histone H3.3 anticorps (ABIN6952331)

Antigène: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Histone H3.3 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-Histone H3.3 anticorps

Specificité: Monoclonal antibody raised in rabbit against histone variant H3.3, using a KLH-conjugated synthetic peptide.

Purification: Protein A purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 1 μg:ChIP
WB 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: PBS, 50 % glycerol, 1 % BSA , 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Histone H3.3

Antigène: Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))

Autre désignation: Histone H3.3

Sujet: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Histone variant H3.3 is preferably present at active genes.

UniProt: P84243