HDAC6 anticorps (N-Term)

N° du produit ABIN6952383

L’anticorps Lapin Polyclonal anti-HDAC6 a été validé pour ELISA, ChIP et ChIP-seq. Il convient pour détecter HDAC6 dans des échantillons de Humain.

Aperçu rapide pour HDAC6 anticorps (N-Term) (ABIN6952383)

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est non-conjugé

Application: ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-HDAC6 anticorps

Épitope: N-Term

Specificité: Polyclonal antibody raised in rabbit against human HDAC6 (Histone deacetylase 6), using two KLH-conjugated synthetic peptides from the N-terminal and the central part of the protein, respectively.

Purification: Peptide affinity purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 3 μg:ChIP
ELISA 1:1,000
WB not recommended

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: PBS, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6

Sujet: HDAC6 (UniProt/Swiss-Prot entry Q9UBN7) belongs to class II of the histone deacetylase family. These enzymes catalyse the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC6 also plays a key role in the degradation of misfolded proteins and in microtubule-dependent cell motility via deacetylation of tubulin and is involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

UniProt: Q9UBN7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling