L’anticorps anti-POLR2A/RPB1 Monoclonal produit chez le Souris a été validé pour WB, ChIP et ChIP-seq. Il convient pour la détection de POLR2A/RPB1 dans des échantillons provenant de Humain.
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Monoclonal antibody raised in mouse against the B1 subunit of RNA polymerase II (polymerase (RNA) II (DNA directed) polypeptide A) of wheat germ. Interacts with the highly conserved C-terminal domain of the protein containing the YSPTSPS repeat.
POLR2A
Reactivité: Humain, Souris, Rat
WB, IF, IHC, ELISA, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ChIP/ChIP-seq 2 μL:ChIP WB 1:500
Restrictions
For Research Use only
Format
Liquid
Buffer
ascites fluid, 0.05 % azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
POLR2A/RPB1 (POLR2A)
(RNA Polymerase II Subunit RPB1 (POLR2A))
Autre désignation
Pol II
Sujet
RNA polymerase II (pol II) is a key enzyme in the regulation and control of gene transcription. It is able to unwind the DNA double helix, synthesize RNA, and proofread the result. Pol II is a complex enzyme, consisting of 12 subunits, of which the B1 subunit (UniProt/Swiss-Prot entry P24928) is the largest. Together with the second largest subunit, B1 forms the catalytic core of the RNA polymerase II transcription machinery.