H2AFZ anticorps (acLys4)

N° du produit ABIN6952410

L’anticorps Lapin Monoclonal anti-H2AFZ a été validé pour WB, IF, ChIP et ChIP-seq. Il convient pour détecter H2AFZ dans des échantillons de Humain.

Aperçu rapide pour H2AFZ anticorps (acLys4) (ABIN6952410)

Antigène: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp H2AFZ est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Détail du produit anti-H2AFZ anticorps

Épitope: acLys4

Specificité: Monoclonal antibody raised in rabbit against histone H2A.Z acetylated at Lys4 (H2A.ZK4ac), using a KLH-conjugated synthetic peptide.

Purification: Protein A purified

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP 0.5-1 μg:ChIP
WB 1:1,000
IF 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: PBS, 50 % glycerol, 1 % BSA , 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur H2AFZ

Antigène: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Autre désignation: H2A.Z

Sujet: Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of H2A.ZK4 is associated with gene activation.

UniProt: P0C0S5

Pathways: Telomere Maintenance