MLL1 anticorps

N° du produit ABIN6952424

Détail du produit anti-MLL1 anticorps

Antigène: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLL1 est non-conjugé

Application: ELISA, Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Specificité: Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.

Purification: whole antiserum

Classe de qualité: ChIP-seq Grade

Immunogène: synthetic peptide

Information d'application

Indications d'application: ChIP/ChIP-seq 2 μL:ChIP
ELISA 1:100 - 1:1,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: serum, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MLL1

Antigène: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Autre désignation: MLL1 (MLL1 Produits)

Synonymes: anticorps Mll, anticorps Mll1, anticorps 6430520K01, anticorps ALL-1, anticorps All1, anticorps Cxxc7, anticorps HRX, anticorps HTRX1, anticorps mKIAA4050, anticorps lysine methyltransferase 2A, anticorps lysine (K)-specific methyltransferase 2A, anticorps Kmt2a

Sujet: MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.

UniProt: Q03164