EZH2 anticorps (AA 1-343)

N° du produit ABIN6952425

L’anticorps Lapin Polyclonal anti-EZH2 a été validé pour WB, IF, ChIP et ChIP-seq. Il convient pour détecter EZH2 dans des échantillons de Humain.

Aperçu rapide pour EZH2 anticorps (AA 1-343) (ABIN6952425)

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EZH2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

Classe de qualité: ChIP-seq Grade

Détail du produit anti-EZH2 anticorps

Épitope: AA 1-343

Specificité: Polyclonal antibody raised in rabbit against the N-terminus (aa1-343) of the mouse EZH2 protein (Enhancer of zeste homolog 2).

Réactivité croisée: Souris

Purification: Protein G purified

Immunogène: recombinant protein

Information d'application

Indications d'application: ChIP/ChIP-seq 2 μg:ChIP
WB 1:1,000
IF 1:1,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: PBS, 0.05 % azide, 0.05 % ProClin300

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur EZH2

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: EZH2

Sujet: EZH2 (UniProt/Swiss-Prot entry Q15910) is a histone-lysine methyltransferase which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression. It is a member of the polycomb group (PcG) family which form multimeric protein complexes and are involved in maintaining the transcriptional repressive state of genes over successive cell generations. The EZH2 activity is dependent on the association with other components of the PRC2 complex (EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP7). EZH2 may play a role in the hematopoietic and central nervous systems. Over-expression of EZH2 is observed during advanced stages of prostate cancer and breast cancer.

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation