SARS-CoV-2 Nucleocapsid anticorps
Aperçu rapide pour SARS-CoV-2 Nucleocapsid anticorps (ABIN6952935)
Antigène
Voir toutes SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified by Protein G.
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Isotype
- IgG2b
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Indications d'application
- WB(1:500-2000), ELISA(1:500-1000)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- ≥ 1 mg/mL
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Buffer
- 0.01M PBS( pH 7.4) with 0.1 % Proclin300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
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Autre désignation
- SARS-CoV-2 Nucleocapsid Protein
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Classe de substances
- Viral Protein
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Sujet
- Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Antigène
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