Catalase anticorps (AA 23-226)

N° du produit ABIN6961050

L’anticorps Lapin Monoclonal anti-Catalase a été validé pour ELISA, IP, IF et FACS. Il convient pour détecter Catalase dans des échantillons de Humain.

Aperçu rapide pour Catalase anticorps (AA 23-226) (ABIN6961050)

Antigène: Catalase (CAT)

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Catalase est non-conjugé

Application: ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: DM9

Détail du produit anti-Catalase anticorps

Épitope: AA 23-226

Purification: Purified from cell culture supernatant by affinity chromatography

Immunogène: Recombinant human CS1 (Ser23-Met226) (ABIN6961075) produced by using human HEK293 cells

Isotype: IgG

Information d'application

Indications d'application: Flow Cyt  1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 50 % Glycerol, PBS, pH 7.4, 0.1 % BSA, 0.1 % Procline 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur Catalase

Antigène: Catalase (CAT)

Autre désignation: CS1

Sujet: Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (By similarity). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (PubMed:23695528).

Poids moléculaire: 37 kDa

ID gène: 57823

UniProt: Q9NQ25

Pathways: Cellular Glucan Metabolic Process, Cell RedoxHomeostasis, Photoperiodism