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LRRC32 anticorps (FITC)

LRRC32 Reactivité: Humain FACS Hôte: Souris Monoclonal GARP5 FITC
N° du produit ABIN7278226
  • Antigène Voir toutes LRRC32 Anticorps
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Reactivité
    • 29
    • 13
    • 9
    • 1
    Humain
    Hôte
    • 20
    • 15
    • 4
    • 1
    Souris
    Clonalité
    • 21
    • 19
    Monoclonal
    Conjugué
    • 21
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Cet anticorp LRRC32 est conjugé à/à la FITC
    Application
    • 20
    • 16
    • 15
    • 10
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
    Clone
    GARP5
    Isotype
    IgG1
    Top Product
    Discover our top product LRRC32 Anticorps primaire
  • Indications d'application
    This antibody preparation has been pre-titrated and quality-tested for flow cytometry using an appropriate cell type. The antibody has been diluted for use at 5 μLper test, defined as the amount of antibody that will stain a cell sample in a final volume of approximately 100 uL. The number of cells within a sample should be determined empirically, but typically ranges between 1x10e5 to 1x10e8 cells.
    Commentaires

    5 uL (0.5 ug)/test

    Restrictions
    For Research Use only
  • Buffer
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    2-8°C protected from light
    Date de péremption
    12 months
  • Antigène
    LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
    Autre désignation
    GARP (LRRC32 Produits)
    Synonymes
    anticorps D11S833E, anticorps GARP, anticorps AI426318, anticorps D11S833Eh, anticorps D7H11S833E, anticorps EG434215, anticorps Garp, anticorps leucine rich repeat containing 32, anticorps LRRC32, anticorps Lrrc32
    Sujet
    The GARP5 antibody reacts with human GARP, also known as LRRC32 or Garpin, an 80 kDa transmembrane protein which acts as a receptor for the latent form of TGF-beta 1 (pro-TGF-beta), preventing its secretion. Specifically, GARP is reported to associate with the pro-domain of TGF-beta 1, known as latency-associated peptide (LAP), which must be cleaved to release the biologically active cy- tokine. The putative role of GARP in sequestering the TGF-beta is important for regulating its activity, as TGF-beta signaling is involved in development and function of Th17, Treg and many other immune cell types. GARP expression has been shown on platelets and at high levels on Foxp3+ Treg cells, where it is proposed to be a phenotypic identifier for activated human Treg cells. The GARP5 antibody may be used for analysis of human GARP by flow cytometry, immunoprecipitation and Western blotting. Please choose the ap- propriate format for each application.
    ID gène
    2615
    Pathways
    Activated T Cell Proliferation
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