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TCR beta anticorps (PE)

Cet anticorps Hamster arménien Monoclonal détecte spécifiquement TCR beta dans FACS. Il présente une réactivité envers Souris.
N° du produit ABIN7278354

Aperçu rapide pour TCR beta anticorps (PE) (ABIN7278354)

Antigène

Voir toutes TCR beta Anticorps
TCR beta (T Cell Receptor (TCR) beta (TCR beta))

Reactivité

  • 53
  • 11
Souris

Hôte

  • 29
  • 24
  • 5
  • 5
  • 1
Hamster arménien

Clonalité

  • 59
  • 4
  • 1
Monoclonal

Conjugué

  • 20
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp TCR beta est conjugé à/à la PE

Application

  • 58
  • 12
  • 9
  • 8
  • 8
  • 7
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Clone

H57-597
  • Purification

    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

    Isotype

    IgG
  • Indications d'application

    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.

    Commentaires

    0.2 mg/mL

    Restrictions

    For Research Use only
  • Buffer

    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    2-8°C protected from light

    Date de péremption

    12 months
  • Antigène

    TCR beta (T Cell Receptor (TCR) beta (TCR beta))

    Autre désignation

    TCR beta

    Sujet

    The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co- receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.

    ID gène

    21577
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