IL-12/IL-23 p40 anticorps

N° du produit ABIN6964022

Détail du produit anti-IL-12/IL-23 p40 anticorps

Antigène: IL-12/IL-23 p40

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-12/IL-23 p40 est non-conjugé

Application: Neutralization (Neut)

Specificité: Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogène: Recombinant mouse IL-12 p70

Clone: C17-8

Isotype: IgG2a

Information d'application

Indications d'application: Neutralization of mouse IL-12 and IL-23 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Date de péremption: 18 months

Références pour anticorps anti-IL-12/IL-23 p40 (ABIN6964022)

Prabhakara, Harro, Leid, Keegan, Prior, Shirtliff: "Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus." dans: Infection and immunity, Vol. 79, Issue 12, pp. 5010-8, (2012) (PubMed).

Lee, Hoeman, Hardaway, Guloglu, Ellis, Jain, Divekar, Tartar, Haymaker, Zaghouani: "Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity." dans: The Journal of experimental medicine, Vol. 205, Issue 10, pp. 2269-80, (2008) (PubMed).

Chackerian, Chen, Brodie, Mattson, McClanahan, Kastelein, Bowman: "Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection." dans: Infection and immunity, Vol. 74, Issue 11, pp. 6092-9, (2006) (PubMed).

Détails sur IL-12/IL-23 p40

Antigène: IL-12/IL-23 p40

Autre désignation: IL12/23 (p40) (IL-12/IL-23 p40 Produits)

ID gène: 16160