ATRX anticorps (C-Term)

N° du produit ABIN6971417

Cet anticorps Lapin Polyclonal détecte spécifiquement ATRX dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour ATRX anticorps (C-Term) (ABIN6971417)

Antigène: ATRX (helicase 2, X-linked (ATRX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATRX est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATRX anticorps

Épitope: C-Term

Attributs du produit: ATRX (alpha thalassemia/mental retardation syndrome X-linked protein, X-linked helicase II, XNP) is a transcriptional regulator and a member of the SWI/SNF family of chromatin remodeling proteins. It contains an SNF2 domain and helicase domain, and a PHD finger. ATRX undergoes cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in interphase gene regulation and chromosomal segregation in mitosis. Mutations of the ATRX gene are associated with an X-linked mental retardation syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. ATRX antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This ATRX antibody was raised against a peptide within the C-terminus of human ATRX.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur ATRX

Antigène: ATRX (helicase 2, X-linked (ATRX))

Autre désignation: ATRX

Poids moléculaire: 300 kDa

NCBI Accession: NP_000480