CoREST anticorps (C-Term)

N° du produit ABIN6971547

L’anticorps Lapin Polyclonal anti-CoREST a été validé pour WB. Il convient pour détecter CoREST dans des échantillons de Humain.

Aperçu rapide pour CoREST anticorps (C-Term) (ABIN6971547)

Antigène: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CoREST est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CoREST anticorps

Épitope: C-Term

Attributs du produit: CoREST (REST corepressor 1, RCOR1) is a corepressor protein recruited by the REST, a neuronal gene-specific transcriptional repressor, to help repress neuron specific gene expression in non-neuronal cell lineages. CoREST is an essential component of the BHC repressor complex that also contains HDAC1, HDAC2, HMG20B/BRAF35, LSD1 (a lysine-4 specific histone demethylase) and PHF21A/BHC80. The Herpes Simplex virus ICP0 protein blocks the repression of viral genes by disrupting the interaction between CoREST and HDAC1/2. CoREST antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This CoREST antibody was raised against a synthetic peptide derived from the C-terminal region of human CoREST.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur CoREST

Antigène: CoREST (RCOR1) (REST Corepressor 1 (RCOR1))

Autre désignation: CoREST

Poids moléculaire: 66 kDa

NCBI Accession: NP_055971

Pathways: Regulation of Hormone Metabolic Process, Chromatin Binding