DMAP1 anticorps (C-Term)

N° du produit ABIN6971584

Détail du produit anti-DMAP1 anticorps

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMAP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Attributs du produit: DMAP1 (DNA Methyltransferase 1 Associated Protein 1) is involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin following replication of DNA at late firing origins. Can also repress transcription independently of histone deacetylase activity. May specifically potentiate DAXX-mediated repression of glucocorticoid receptor-dependent transcription. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Participates in the nuclear localization of URI1 and increases its transcriptional corepressor activity. DMAP1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide within the C-terminal region of human DMAP1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur DMAP1

Antigène: DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Autre désignation: DMAP1 (DMAP1 Produits)

Synonymes: anticorps Afu4g07380, anticorps T8I13.5, anticorps DNMAP1, anticorps DNMTAP1, anticorps EAF2, anticorps MEAF2, anticorps SWC4, anticorps zgc:55593, anticorps dnmap1, anticorps dnmtap1, anticorps eaf2, anticorps meaf2, anticorps swc4, anticorps 1500016M21Rik, anticorps Dmtap1, anticorps mKIAA1425, anticorps DNA methyltransferase 1-associated protein DMAP1, anticorps DNA methyltransferase 1-associated protein 1, anticorps DNA methyltransferase 1 associated protein 1, anticorps myb-like transcription factor family protein, anticorps DNA methyltransferase 1 associated protein 1 L homeolog, anticorps AFUA_4G07380, anticorps NFIA_108840, anticorps ACLA_046700, anticorps CpipJ_CPIJ017959, anticorps Bm1_47540, anticorps PMAA_026820, anticorps AFLA_112450, anticorps TSTA_072020, anticorps BDBG_02603, anticorps AT2G47210, anticorps CpipJ_CPIJ007438, anticorps DMAP1, anticorps dmap1, anticorps dmap1.L, anticorps Dmap1

Poids moléculaire: 60 kDa

NCBI Accession: NP_061973