FOXL2 anticorps (N-Term)

N° du produit ABIN6971660

Détail du produit anti-FOXL2 anticorps

Antigène: FOXL2 (Forkhead Box L2 (FOXL2))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXL2 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: FOXL2 (forkhead box L2, BPES, PFRK, POF3, BPES1, PINTO) is a transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. FOXL2 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogène: This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur FOXL2

Antigène: FOXL2 (Forkhead Box L2 (FOXL2))

Autre désignation: FOXL2 (FOXL2 Produits)

Synonymes: anticorps BPES, anticorps BPES1, anticorps PFRK, anticorps PINTO, anticorps POF3, anticorps AU045128, anticorps Pfrk, anticorps FOXL2, anticorps zgc:136549, anticorps foxl2, anticorps FoxL2, anticorps foxL2, anticorps forkhead box L2, anticorps forkhead box L2a, anticorps forkhead box L2 S homeolog, anticorps forkhead transcription factor L2, anticorps foxl2 protein, anticorps fork-head box L2 transcription factor, anticorps FOXL2, anticorps Foxl2, anticorps foxl2a, anticorps foxl2, anticorps foxl2.S, anticorps LOC751846, anticorps foxL2

Poids moléculaire: 40 kDa

NCBI Accession: NP_075555

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity