Histone H2A anticorps

N° du produit ABIN6971753

Cet anticorps Lapin Polyclonal détecte spécifiquement Histone H2A dans WB et ChIP. Il présente une réactivité envers Saccharomyces cerevisiae et Schizosaccharomyces pombe.

Aperçu rapide pour Histone H2A anticorps (ABIN6971753)

Antigène: Histone H2A

Reactivité: Saccharomyces cerevisiae, Schizosaccharomyces pombe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2A est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Détail du produit anti-Histone H2A anticorps

Attributs du produit: Histone H2A is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3 and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, it is responsible for establishing higher-order chromatin structure. Chromatin is subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, they play a major role in regulating gene expression. Histone H2A antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation and Western blot, it has been shown to react with Budding Yeast and Fission Yeast samples.

Purification: Protein A Chromatography

Immunogène: This Histone H2A antibody was raised against recombinant yeast histone H2A.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur Histone H2A

Antigène: Histone H2A

Poids moléculaire: 14 kDa

NCBI Accession: NP_010511