H2AFJ anticorps (AA 122-129)

N° du produit ABIN6971761

Détail du produit anti-H2AFJ anticorps

Antigène: H2AFJ (H2A Histone Family, Member J (H2AFJ))

Épitope: AA 122-129

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp H2AFJ est non-conjugé

Application: Western Blotting (WB), Dot Blot (DB)

Attributs du produit: Histone H2A is one of the core components of the nucleosome. The nucleosome is the smallest subunit of chromatin and consists of 147 base pairs of DNA wrapped around an octamer of core histone proteins (two each of Histone H2A, Histone H2B, Histone H3and Histone H4). Histone H1 is a linker histone, present at the interface between the nucleosome core and DNA entry/exit points, and is responsible for establishing higher-order chromatin structure. Histone H2A.J is a histone H2A variant, a protein similar to canonical H2A but with different molecular identity and unique functions. Histone H2A.J, which is found only in mammals, is shown to be associated with senescence, accumulating in senescent fibroblasts and promoting expression of inflammatory genes. Therefore, H2A.J may contribute to chronic inflammation and age-related diseases. Histone H2A.J antibody (pAb) was raised in a Rabbit host. It has been validated for use in Dot blot and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogène: This antibody was raised against a peptide comprising amino acids 122-129 of human Histone H2A.J.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Détails sur H2AFJ

Antigène: H2AFJ (H2A Histone Family, Member J (H2AFJ))

Autre désignation: Histone H2A.J (H2AFJ Produits)

Synonymes: anticorps H2AJ, anticorps H2a/j, anticorps H2A-IX, anticorps H2AFJ, anticorps E130307C13, anticorps h2afj, anticorps H2A histone family member J, anticorps H2A histone family, member J, anticorps histone H2A.J, anticorps H2A histone family member J L homeolog, anticorps H2AFJ, anticorps H2afj, anticorps LOC103690002, anticorps h2afj.L

NCBI Accession: NP_808760